bullyxtreme Chapter 388 Debate
Chapter 388 Debate
Tang Yuze stood at the back door of the auditorium, his figure as straight as a pine tree.
Faced with Professor Zhong Qi's provocative and challenging questions, he did not show any fear on his face. Instead, a very faint, slightly mocking arc appeared at the corner of his mouth.
The air in the entire auditorium seemed to be sucked dry, and everyone held their breath, waiting for the answer from this student who dared to challenge Professor Zhong's authority.
Will you admit to bragging in an embarrassing manner, or create a miracle?
"Professor Zhong, the technical difficulties in using the single-molecule FRET technique you mentioned to observe the heterogeneity of the folding pathway of the prion protein PrP lie primarily in eliminating background noise and the potential impact of specific labeling sites on the protein's native conformation. Especially when observing proteins like PrP that are prone to aggregation and conformational transitions, the introduction of the fluorescent group itself may become a variable in the folding pathway, causing the observed 'heterogeneity' to be partially due to experimental intervention rather than a completely natural kinetic process."
Tang Yuze spoke. His voice was still steady, but it carried a clear power that pierced through the fog and instantly caught everyone's attention.
He spoke slowly, ensuring that every word could be heard clearly, and his wording was precise, perfectly in the tone of a professional journal discussion forum.
"As for the pitfalls of data analysis, traditional Gaussian fitting models have limitations when dealing with polymorphic folding intermediates, and can easily discretize continuously changing dynamic processes into a few isolated 'states'. A better solution would be to use hidden Markov models or Bayesian inference combined with maximum likelihood estimation, but this requires extremely high computing resources and initial parameter settings, which is currently a recognized bottleneck in the field."
He spoke eloquently, not only accurately pointing out the difficulties, but also highlighting the solutions currently being attempted by the academic community and their inherent new problems.
"Regarding the core argument of 'the association between the free energy landscape of folding intermediates and disease susceptibility,' I believe that simply attributing disease susceptibility to the stability of one or more folding intermediates on the free energy landscape may oversimplify the complexity of living systems. In vivo environments differ significantly from in vitro experimental conditions. Physiological factors such as molecular chaperones, cell membrane environments, and co-translational folding can significantly reshape the so-called 'free energy landscape.' Ignoring these factors and only discussing 'associations' under in vitro simulations will likely lead to misleading conclusions that fail to truly reflect the pathophysiological mechanisms of disease."
Since Professor Zhong Qi insisted on showing off with these professional knowledge, Tang Yuze would accompany him to show off and tell him that not every college student is someone he can look down upon.
Quiet.
Deathly silence!
If you could hear a pin drop before, now even the sound of air flowing seems to have disappeared.
All the students in the audience, including those who did not understand the specific content at all, understood one thing from Tang Yuze's calm demeanor, fluent and precise expression, and the sudden change in Professor Zhong Qi's expression on the stage.
This boy is not talking nonsense.
What he said is probably right!
Moreover, he even criticized the limitations of Professor Zhongqi's research ideas!
“Oh… damn!”
Luo Mingcheng was the first to react. He was so excited that he almost jumped out of his chair. He covered his mouth tightly to prevent the scream from breaking through his throat, but the excitement and disbelief in his eyes almost overflowed.
Although he didn't understand what Tang Yuze was saying at all, judging from Zhong Qi's expression, Tang Yuze must have answered all the questions correctly.
Luo Mingcheng pinched his thigh hard.
It hurts! This isn't a dream!
His buddy Tang Yuze turned out to be a hidden biology expert?
After a brief moment of silence, there was an uproar like a volcanic eruption!
"Oh my god! He actually answered it?!"
"That sounds really reasonable! It breaks down the professor's questions!"
"He even refuted the professor's point! That's awesome!"
"Who is this guy? Which hospital is he from? He's so awesome!"
The audience was instantly boiling with excitement. The previously suppressed grievances and anger now turned into indescribable excitement and excitement.
Tang Yuze's remarks were like a flash of lightning that cut through the darkness. Not only did they respond to the difficulties, but to a certain extent, they also fought back against Zhong Qi's arrogant attitude on behalf of all of them!
The expressions of the school leaders in the front row were even more wonderful.
The Dean of the Academic Affairs Office kept his mouth open for a long time, his eyes filled with shock and a strange sense of relief.
Fortunately, fortunately there was such a student who stood up, otherwise I really don’t know how this situation would end today.
Yang Yi, the dean of the School of Bioengineering who was sitting next to him, was extremely surprised at first, and then a fiery light burst out in his eyes!
He turned his head suddenly and asked the Dean of Academic Affairs next to him in a low voice.
"Old Liu, this student! Which college is this student from? We definitely don't have anyone like him in our School of Biological Engineering! How could such a talent, with such deep thinking, be buried in other majors?! We must dig him up! We must dig him up at all costs!"
"Wait a minute, I remember this student's name is Tang Yuze, and he's registered as... a student in the School of Computer Science, majoring in Electronic Information."
The director of the Academic Affairs Office was also confused, but he remembered that he had seen Tang Yuze before when he was dealing with the subway voyeurism incident. He quickly looked through the roster in his hand to confirm and responded in a low voice.
"Strange, how can a computer science student know so much about the frontiers of biology?"
"Computer Science College? Interdisciplinary genius! Is this a true interdisciplinary talent?
"Old Liu, after the lecture, no, we must find a way to transfer him to our School of Biological Engineering!"
Upon hearing this, the light in Dean Yang Yi's eyes became even brighter, as if he had discovered a priceless treasure.
On the podium, Professor Zhong Qi's expression had completely changed from the initial ridicule and displeasure to shock and embarrassment.
He could never have imagined that a seemingly ordinary undergraduate could respond to his questions so accurately and even critically!
This is definitely not just understanding, it clearly shows a very deep understanding and independent thinking!
He opened his mouth and wanted to refute, but found that the problems pointed out by the other party were exactly the difficulties that the field was reflecting on and trying to break through. Even the issue of differences between internal and external environments raised by the other party was one of the questions raised by the reviewers of his recent paper.